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In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

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In conclusion, lithopone suppliers play a critical role in the supply chain of this important white pigment. Their expertise, consistent quality control, and wide range of product offerings make them an indispensable partner for manufacturers who rely on lithopone in their products. By working closely with suppliers, manufacturers can ensure that they receive high-quality lithopone that meets their specific requirements and helps them create products that stand out in the market.

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  • In addition to quality, CL77891 also offers a wide range of titanium dioxide products to cater to different applicationsclcl 77891 titanium dioxide supplier. Whether you need titanium dioxide for paints, coatings, plastics, or other industrial uses, CL77891 has the right product to meet your specific requirements. With a comprehensive product portfolio and the ability to customize products to meet individual needs, CL77891 is well-positioned to serve a diverse range of industries and applications.